Bioinks are materials that mimic an extracellular matrix environment to support the adhesion, proliferation, and differentiation of living cells.
From GelMA to Collagen and from Hyperelastic Bone to Graphene, Allevi offers the widest range of material capabilities.
On the Allevi platform, you can 3D bioprint functional tissues, complex geometries, or physiologically relevant models.
Hydrogels, such as gelatin methacrylate, alginate, PEGDA, and collagen give you the ability to print cell-laden structures with soft tissue cell types.
These first in class products allows cells to be mixed with a matrix that covalently crosslinks when exposed to light or a chemical compound during printing.
Using the FRESH method with either alginate or collagen, you are able to print extremely complex and thin walled structures for more relevant soft tissue models.
These biocompatible materials can be printed alongside cells to ensure proper cell dispersion and physiological relevance within a tissue.
Biocompatible thermoplastics such as polycaprolactone, PLGA, and Hyperelastic Bone are specifically developed and optimized for 3D bioprinting of hard tissues. These polymers offer enhanced control over mechanical properties of final 3D structures and are used when printing harder tissues such as bone and cartilage.
Thermoplastics may be used on their own or printed alongside hydrogels and cells.
When combined with printing methods, such as the FRESH protocol, users are able to print complex geometries with tunnels for nutrient flow or drug delivery.
These sacrificial bioinks are also useful when created body-on-a-chip or organ-on-a-chip models to allow for media flow through the tissues.
These materials can be printed alongside hydrogels and other extra cellular matrices.
Materials with high conductivity such as graphene can be combined with hydrogels and cells for applications in cardiac and neural tissues where conductivity is an important material property for functionality.
These conductive materials can also be used along electric systems for biomedical models and applications.